Kisspeptin‑10 is a naturally derived decapeptide that activates the KISS1R (GPR54) receptor, triggering release of GnRH and subsequently luteinizing hormone (LH) and follicle‑stimulating hormone (FSH). It plays a pivotal role in reproductive hormone regulation, puberty initiation, and shows emerging potential in fertility, sexual desire, and metabolic pathways.
Stimulates gonadotropin release (LH/FSH) in men and women during preovulatory phase
Key regulator of puberty and reproductive axis via GnRH activation
Potential therapeutic utility in infertility and reproductive disorders
Investigational benefits in libido, mood, metabolism, and modest tumor‑suppressive functions via KISS1 signaling
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