ARA-290 – 10mg – Super Human Peptides

ARA-290 – 10mg

Description

Description

ARA-290 (also known as Cibinetide) is a synthetic 11-amino acid peptide engineered from the helix-B surface domain of erythropoietin (EPO). Designed to capture EPO’s tissue-protective properties without stimulating red blood cell production, it selectively activates the Innate Repair Receptor (IRR). Clinical and preclinical research highlights its potential for neuroprotection, anti-inflammatory signaling, and nerve regeneration. Currently for research use only.

PURITY

99% HPLC

RUO

Research Use Only
Not for human or veterinary use.

Price: $60.00

Innate Repair Receptor (IRR) Activation — Selectively binds the IRR — a cell surface complex found on nerve, immune, and vascular cells — triggering localized tissue-protective and anti-inflammatory signaling without engaging EPO’s hematopoietic pathway.
Neuroprotection & Nerve Regeneration — Preclinical and early clinical studies show ARA-290 may reduce neuropathic pain, support corneal nerve fiber regeneration, and promote functional recovery following peripheral nerve injury — with particular interest in diabetic and sarcoidosis-related neuropathy.
Targeted Anti-inflammatory Action — Rather than broadly suppressing immunity, ARA-290 rebalances local inflammatory responses — reducing pro-inflammatory cytokines and shifting immune cells toward a tissue-repair profile, with reductions in markers like CRP observed in small trials.
Safe EPO-Derived Profile — By isolating EPO’s protective domain while eliminating sequences responsible for erythropoiesis, ARA-290 avoids the cardiovascular risks of EPO therapy (hypertension, thromboembolism) while retaining its regenerative benefits, with high subcutaneous bioavailability (>85%).